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Introduction
Viferon 500000 is a drug used for infectious and bacterial diseases. It is used in dentistry, pediatrics, gynecology, venereology to maintain the immune system and fight viruses.
Prescribing the drug
The use of Viferon 500,000 IU suppositories is prescribed in addition to the main treatment:
- SARS;
- herpes;
- cytomegalovirus;
- sepsis;
- meningitis;
- mycoplasmosis;
- enterovirus;
- influenza and parainfluenza;
- pneumonia;
- acute and chronic inflammation of the liver.
If a person is in close contact with the patient, he is also prescribed a course of using Viferon 500,000 IU to protect against infection with the virus and maintain immunity.
Characteristics of the drug
The immunomodulatory and antiviral medication Viferon 500000 is made in the form of rectal milky suppositories.
Component and main active ingredient
The main ingredient of the drug is interferon alpha-2b human recombinant 500,000 IU. As additional components in suppositories contain:
- vitamin E (alpha-tocopherol acetate) – 0.055 g;
- vitamin C (ascorbic acid) – 0.0081 g;
- sodium salt of ascorbic acid (sodium ascorbate) – 0.0162 g;
- disodium edetate dihydrate – 0.0001 g;
- polysorbate 80 – 0.0001 g;
- cocoa butter and confectionery fat – up to 1 g.
Size and shape of rectal suppositories
Viferon 5,000,000 rectal suppositories have a bullet-shaped shape with a small funnel-shaped depression on one side and a narrowing at the other end. The diameter of the candle does not exceed 10 mm.
Package
The packaging is a cardboard box containing 10 suppositories, each stored in a personal carefully closed contour cell.
Pharmacokinetics and pharmacodynamics
Pharmacodynamics: Viferon 500,000 IU is characterized by clearly manifested antiviral, immunomodulatory and antiproliferative properties.
The main active element, interferon alpha-2b, is a highly purified protein obtained through recombinant DNA technology and using a genetically engineered E. coli strain. The component is identical to human leukocyte interferon alpha-2b. It contains 165 amino acids.
The immune system is supported by interferon alfa-2b:
- the component stimulates the genes responsible for the suppression of viruses in an infected cell;
- prevents the reproduction of virus cells;
- disrupts the synthesis of viral DNA, RNA and proteins;
- stimulates the growth of effector proteins;
- increases the activity of macrophages responsible for the absorption of viral, harmful, bacterial, dead and dying cells;
- stimulates cytotoxic dynamism of lymphocytes;
- conducts anticancer activity.
Vitamin E contained in the medication increases the antiviral and immunomodulatory activity of the main active ingredient – interferon alpha-2. Vitamin E is a strong antioxidant that also has anti-inflammatory, membrane-stabilizing and regenerating properties.
Vitamin C ensures the normal functioning of connective and bone tissue, has restorative and antioxidant properties.
Sodium ascorbate acts as an oncoprotector, preventing free radicals from accumulating in the body. Disodium edetate dihydrate enhances the body’s absorption of the remaining components of the suppositories.
Pharmacokinetics: The effective activity of the main ingredient is observed within 12 hours after rectal administration. After that, its amount in the blood decreases, which indicates the need for its reuse.
Instructions and dosages
Candles are administered rectally in the prescribed dosage, which is determined by the doctor depending on the disease.
In addition to the complex treatment of chronic hepatitis B, C, D in children and adults:
- up to six months: 300,000–500,000 IU per day;
- in half a year – a year: 500,000 IU per day;
- from one year to seven years: 300,000 IU per 1 m2 of body surface area per day;
- over seven years: 500,000 IU per m2 of body surface area per day.
Candles are administered twice a day every half a day for the first 10 days. Then three times a week every other day for six months to a year.
- Children over 7 years old: 1 suppository twice a day every 12 hours. We recommend to figure out whether it is possible to take Viferon candles for children up to a year .
In the complex treatment of chlamydia, cytomegalovirus, ureaplasmosis, trichomoniasis, gardnerellosis, papillomavirus infection, bacterial vaginosis, recurrent vaginal candidiasis, mycoplasmosis, Viferon 500,000 IU is used:
- Adults, including pregnant women, 1 suppository 2 times a day every 12 hours for 5-10 days. Several courses can be assigned with breaks of 5 days.
For the complex therapy of primary or recurrent herpetic infection of the skin and mucous membranes of a localized form, mild and moderate course, the drug is prescribed:
- Pregnant women in the 2nd trimester (from 14 weeks) 1 suppository every 12 hours twice a day for 10 days. After that, 1 suppository every 12 hours twice a day, 2 times a week for 10 days. Then, after 4 weeks, prophylaxis is carried out using Viferon at a dosage of 150,000 IU for 5 days with a repetition of the course every 4 weeks.
In the complex treatment of acute respiratory viral infections, including influenza and diseases complicated by a bacterial infection, Viferon 500,000 IU is prescribed:
- Adults: 1 suppository rectally twice a day every 12 hours daily for 5-10 days.
We use medicine for children
Viferon with a dosage of 500,000 IU can also be prescribed for children.
At what age should the drug be administered?
The drug is used for children from birth, but in permitted dosages.
Norms and rules of application
Children can be prescribed a dosage of 500,000 IU as a last resort, for the treatment of uncomplicated infections in premature infants and up to six months there are suppositories with a dosage of 150,000 IU.
In the complex therapy of various types of hepatitis in a chronic form, the drug is prescribed according to the scheme:
- For a child from birth to six months. 1 candle 500,000 IU per day or 2 candles 150,000 per day (one every 12 hours).
- From 6 months to 2 years. 500,000 IU per day.
- For older kids. For children older than 2 years, the daily dosage of the drug is calculated according to the scheme: up to 7 years: 300,000 IU per m2 of body surface area per day; over 7 years: 500,000 IU per m2 of body surface area per day.
Use in early and late pregnancy: frequency and duration of administration
In the first trimester (up to 14 weeks), the drug should not be used. After 14 weeks of pregnancy, the dosage and time frame of therapy is determined by the attending physician. Viferon is usually prescribed at a dosage of 500,000 IU twice a day, one candle for a week.
Existing contraindications
Viferon has practically no contraindications, due to its safe composition:
- individual intolerance to one or more elements of candles;
- pregnancy up to 14 weeks.
Side effects
Possible manifestations of allergic reactions: itching, redness, urticaria, rash.
How they interact with other drugs
Viferon interacts well with all medications, including antibiotics, hormonal agents and chemotherapy drugs.
Price
Viferon suppositories at a dosage of 500,000 IU in Russian pharmacies cost from 354 rubles.
Vacation and storage conditions
It is dispensed from pharmacies without a doctor’s prescription.
To preserve the properties of suppositories, it is necessary to provide a dark, dry place inaccessible to children, with a temperature of 2-8 degrees. The refrigerator is best for storing suppositories. It is forbidden to freeze the drug, in order to avoid loss of effectiveness.
Shelf life – 2 years from the date of issue.
Reviews about the medicine
Alexandra, 32 years old:My daughter is 9 years old, our doctor always prescribes Viferon suppositories for colds, flus, sore throats . Symptoms become less pronounced gradually and on the 2nd day they practically disappear. The temperature drops, lethargy and weakness disappear, the fever ceases.
After 5-7 days, complete recovery occurs. Good candles, without hesitation, I buy, if they are appointed, it has already been checked – it works.
Marina, 45 years old: My doctor wrote me a prescription for taking antibacterial agents, vitamins, cough tablets and nasal drops when I had the flu. Viferon was also prescribed in addition to treatment. I applied, as it was prescribed, for 5 days, I never missed it.
But in the first three days I did not notice any changes, and on the fourth day I recovered, no symptoms remained. I didn’t understand if the candles worked like that or other medicines. But I am of the opinion that everything together gave such a result. The main thing is that I’m healthy.
Andrey, 50 years old:I was worried about painful urination, such a delicate problem, I could not see a doctor for a long time and dragged it out. When I got tired of enduring, I went to the doctor and was diagnosed with “urethritis”. They prescribed a whole list of medicines, including Viferon. Put candles 2 courses for 5 days. I noticed improvement on the second day. It’s all over, I’m glad. Do not pull with a trip to the doctor, I do not advise.
Asya, 25 years old: I always have a hard time with the flu. I talked a little with the sick person – everything, I immediately fell ill, the temperature was under 40, the body aches unbearably, the fever is so that the teeth are chattering.
I take antipyretic and Viferon suppositories from the first day of illness, because the sooner you start using, the better they help.
Candles are quickly absorbed and the effect is almost immediately noticeable. Another plus for me personally is that with gastritis, many drugs irritate, cause pain and frustration, and Viferon is not in tablets. Therefore, who has gastritis – I recommend Viferon.
Zhenya, 29 years old:All my life, as long as I can remember, herpes appears, and this is painful, ugly and unpleasant. Usually I immediately smear with ointment, they help, and not bad, but how much can I have?
I want to get rid of the virus itself. I read the instructions for Viferon candles, it says that they have a positive effect on the immune system and fight many viruses and bacteria. I bought Viferon in a pharmacy, and I am very happy with my decision. For a year now, herpes has not appeared, and I hope it will not appear.
Daria, 23 years old:I went to a gynecologist for a preventive examination and accidentally discovered chlamydia. I was in shock, scared. But I was told that the form is chronic, so I did not notice any symptoms.
If this disease is started, in the future there will be problems in a feminine way. They prescribed antibiotics, vitamins, Viferon in candles. I put it twice a day, it is very convenient that they are quickly absorbed and then you walk for 12 hours. I didn’t have to add anything to work.
Anna, 33 years old: I have two aged children. One fell ill – immediately the second picks up, the first is cured – the second infects, and so on in a circle. Therefore, for several years now I have been turning to Viferon for help, as soon as ARVI, acute respiratory infections, influenza occur.
Immediately at the first symptoms, I put candles for the whole family: the main patient for a speedy recovery, the rest – to strengthen the immune system and not get infected. I like that Viferon works almost immediately, on the second or third day we are on the mend, the child is more cheerful, appetite wakes up, then I calmly exhale.
After a couple of years, a complete recovery occurs. The only downside to candles is that they melt quickly. Once I forgot to put it in the refrigerator, it was hot at home, it melted, I could not insert it, the candle slipped out.
And when a candle comes out of the refrigerator, it is convenient to introduce it, it feels smooth and dry at first. The main thing is not to hold it in your hand for a long time, it starts to melt. The price is very affordable, there are no side effects, there are no harmful components, it answers all my requests. I recommend Viferon to everyone.
