Under the abbreviation HPV, the human papillomavirus is hidden, in another way – papillomavirus. The variety of viruses in this group is so great that they are classified by type, and each of them has its own “number” depending on what kind of danger it poses.
Unfortunately, HPV type 45 is classified as a factor of high oncogenicity. In other words, the presence of this virus in a woman’s body increases the likelihood of tumors.
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Features of human papillomavirus infection
HPV type 45 is rare in women. However, if this happens, treatment is required urgently. Its activity in the female body largely depends on the body’s immune system. There are cases when the immune system literally drives the virus away without outside help. But this doesn’t happen often.
To begin with, it should be said that infection with HPV type 45 is closely related to promiscuity. The source of the disease is the cells affected by the virus and the mucous membrane of a sick person. Once in a healthy body, they cause the appearance of genital warts.
The process of infection with this type of virus is as follows:
- Through microtraumas and cracks in the genital organs, the infection penetrates into a healthy body.
- Once in a new organism, the virus collides with immunity. If the defense system is normal, it will safely neutralize the virus. Otherwise, the pathogen moves on.
- The next “stop” of the virus is the basal layer of the epithelium of the cervix.
- Having penetrated the cells, the virus begins to integrate into the chromosomes of the cells of the body and interfere with their work. Cells begin to divide uncontrollably, leading to the formation of papillomas, and later cancer.
Infection can be represented in three stages:
- The occurrence of genital warts.
- Dysplasia of the cervix.
- Cervical cancer.
Ways of entry of infection into the body
Despite the fact that there are several ways of infection, they are all directly related to unprotected intercourse.
- Unsafe sex.
- Petting with close contact with the genital mucosa of the virus carrier.
- Congenital acquisition of the virus by the child from the mother (during childbirth).
papillomavirus symptoms
The symptomatology of HPV type 45 has several features, which is why both diagnosis and timely access to a doctor and treatment are difficult.
Firstly, the symptoms of papillomavirus resemble those of other diseases of the genitourinary system, including STIs.
Secondly, the virus may not manifest itself for a long time.
Thirdly, in many cases, infection is accompanied by diseases such as syphilis, herpes, chlamydia, gonorrhea, trichomoniasis.
- The appearance of uncharacteristic vaginal discharge with an unpleasant odor.
- Discomfort, burning, itching in the genital area.
- The appearance of genital warts in the vagina, anus or mouth (if there was vaginal, anal or oral contact, respectively).
- Pain, cramps, discomfort during urination, defecation and sexual intercourse.
- With advanced disease, there may be bleeding from the genitals or vaginal bleeding.
How dangerous is the virus for women and men
The danger of HPV, in the first place, is that the symptoms do not always appear immediately.
With delayed treatment or poor-quality diagnosis (for example, a concomitant sexually transmitted disease was detected, and a woman is treated only for it), malignant tumors are formed.
Cells whose DNA has been invaded by the virus begin to invade healthy cells and cause them to divide. HPV affects unaffected tissue areas only during the period when favorable conditions have been created for that.
When the DNA of diseased and healthy cells combines, a condition called koilocytosis occurs. The “good” cells degenerate into bad ones, and an invasive cancer condition develops. We recommend that you familiarize yourself with the material: papilloma ICD 10 .
Accordingly, a woman loses reproductive function and receives high risks of death.
Diagnosis of the virus in the female body
Most often, papillomavirus infection is detected by chance during a routine examination by a gynecologist. That is why a preventive visit to the antenatal clinic is so important for the health and life of a woman.
In addition, other diagnostic methods are effective:
- PCR (polymerase chain reaction) – analysis of biological material for the presence of pathogens. This method has one significant drawback: it also detects HPV types 31 and 35 , but it cannot separate them from each other.
- Digen test . The most accurate and modern way to detect HPV type 45, while setting the severity. With the test, you can determine how much the virus has spread to healthy tissues.
- Colposcopy .
- Cytological and histological examination of the formation (growth).
- Biopsy of the emerging outgrowth.
Treatment
If HPV type 45 has been detected, a consultation with a gynecologist, urologist, or dermatovenereologist may be required. There is no single way to get rid of the virus once and for all, so urgent complex therapy is required. Its components are:
- Surgical intervention.
- Medical treatment.
- Strengthening immunity.
Surgical intervention involves the removal of papillomas by surgery. Laser removal , cryodestruction (removal with liquid nitrogen), radio wave method, electric knife are used .
If papillomas are removed at stages 1 and 2 of the disease, it ends, in general, safely for the patient, but she will have to take drugs to strengthen her immune system throughout her life. If the disease has reached stage 3, the consequence is infertility.
Drug treatment is aimed at the “extermination” of the virus. The basis of therapy is the use of antiviral drugs (Interferon, Cycloferon, Groprinosin), the use of creams (Bonafton, Kondilin), vaginal suppositories (Viferon, Panavir) and herbal medicine (treatment with herbal teas and tinctures).
Alternative treatment
Some traditional medicines are remarkably effective, but it’s important to know two things:
- Treatment with folk remedies should be complementary to drug therapy or a surgical method.
- The use of this or that remedy should be agreed with the doctor.
Proved better than others:
- Tea tree oil (castor). An aqueous solution is prepared in a ratio of 1: 1, in which special dressings are wetted and applied to the affected area.
- Washing with tar soap.
- Night compresses of petroleum jelly, vinegar, onion juice and wheat flour.
papillomavirus in pregnant women
Detection of papillomavirus in pregnant women is the most difficult and dangerous case. The fact is that the immunity of a pregnant woman noticeably weakens, and if shortly before pregnancy the virus “clung” to her body, during this period it can manifest itself.
If HPV type 45 is detected during pregnancy, this does not mean at all that the pregnancy will have to be terminated. Indications in this case are to be observed by a doctor for all 9 months and especially carefully monitor your health.
Special drug therapy is required in the third trimester. It consists in taking “Cycloferon”, “Poludan” and “Prodigiozan”.
Disease prevention
Preventive measures for papillomavirus 45 strain are as follows:
- Absence of promiscuity, use of contraceptives.
- Regular preventive examination by a gynecologist.
- Healthy eating, giving up bad habits, the correct daily routine.
- Sufficient physical activity (sports, walking).
- Avoidance of stressful situations, overvoltages, overloads.
- Taking multivitamins and immune boosters.
- Careful attitude to one’s health, fulfillment of all prescriptions of doctors, aftercare of all diseases.
- Vaccination with Gardasil and Cervarix at the age of 9 to 25 years.
Despite significant advances in medicine, cures for all diseases have not yet been invented. Some diseases, although they occur more and more often, they do not want to talk about their “weak points”.
Doctors are unable to help a person who does not take care of his own health, ignores recommendations and neglects treatment. Sometimes the diagnosis for the patient is shocking, and to prevent this from happening, it is important to take care of yourself. It is better to be safe than to regret all your life about lost time and opportunities. Watch your health!
