Allokin-Alpha: how to make an injection and what to dilute the drug with, the drug’s release form, contraindications

Viruses infect a person, causing diseases such as herpes, hepatitis and papillomas. For their effective treatment, a new generation drug, Allokin-Alpha, was created.

This is an antiviral, immunomodulatory drug based on a natural component obtained by chemical synthesis. The drug is well tolerated and has almost no side effects, it can be safely combined with other medicines.

Indications for use

Allokin-Alpha is used for the following diseases:

• chronic papillomavirus infection provoked by oncogenic types of the virus;
• recurrent chronic herpes types 1 and 2;
• moderate form of hepatitis B (as part of complex therapy);
• subclinical and clinical lesions of the anogenital region and cervix of papillomavirus infection;
• plantar and flat warts;
• cervical erosion.

Characteristics of the drug

Allokin-Alpha is a new generation antiviral agent that has a number of its own features and properties.

Dosage form

The drug is available in the form of a lyophilizate for the manufacture of a solution that is injected subcutaneously. The lyophilized powder is hygroscopic and white in color.

Composition and main active ingredient

One ampoule of Allokin-Alpha contains 1 mg of alloferon, which is also the main active ingredient. Alloferon is a natural cytokine-like peptide obtained by chemical synthesis. It has a pronounced antitumor and antiviral activity.

Pharmacological properties

Alloferon is an oligopeptide. According to the pharmacological action, it has much in common with alpha interferon. Alloferon is an effective inducer of interferon synthesis and an activator of natural killers.

It stimulates cytotoxic lymphocytes to recognize defective cells and promotes the restoration of T-cell immunity. The experiments revealed a high efficiency of the impact on infections provoked by human papillomaviruses, hepatitis C and B, influenza, herpes types 1 and 2.

General effect on the body

Allokin-Alpha is non-toxic, has no carcinogenic and mutagenic effects, allergenic properties, does not affect the reproductive function and toxic effects on the hematopoietic organs.

Excluded hepato-nephrotoxic and embryotoxic effects. The drug has a positive effect on interferon and immune status, is not addictive.

The immunomodulatory and antiviral activity of the drug improves the quality of life of the patient, namely:

• the relapse period is halved;
• the remission period is doubled;
• the severity of recurrence is reduced.

The drug is activated only in infected cells and is not introduced into the DNA, it is excreted from the body unchanged.

Medication packaging (ampoules)

Allokin-Alpha is available in colorless glass ampoules, each of which contains 1 mg of the drug. Ampoules in the amount of 10, 5, 3, 2 or 1 are placed in a blister pack. One or two blister packs are placed in a small cardboard box along with instructions.

The mechanism of action on the HPV virus

When using the drug for the treatment of human papillomavirus infection, the elimination effect was first obtained in 90% of cases with cervical dysplasia after half a month.

Allokin-Alpha activates natural killers that destroy virus-infected cells and their contents. The drug acts localized, directly in the focus of inflammation, which avoids unnecessary reactions of the immune system.

Instructions for use

When using the drug, you should know the dosage and norms, as well as be able to properly inject. This will help not harm your health and quickly recover from the disease.

How to dilute the medicine for injections: norms and dosages, is saline suitable?

Before preparing the medicine for injection, you must thoroughly wash your hands with antibacterial soap or treat them with alcohol. Then you should draw 1 ml of a 0.9% sodium chloride solution (physiological saline) into the syringe and inject it directly into the powder ampoule.

The contents must be shaken until a homogeneous liquid is obtained. Then the medicine must be drawn from the ampoule into the syringe. The dosage of the drug per injection is 1 mg.

Rules for administering the drug intramuscularly

In order to properly inject, you must perform the following steps:

• Carefully treat the needle insertion site with a cotton swab soaked in alcohol or an alcohol wipe.
• With your left hand, fold the skin into a fold.
• Insert the needle right at the base of the crease at an angle of 45 degrees to a depth of 2 cm.
• Inject the drug evenly and slowly.
• After there is no medicine left in the syringe, you need to carefully remove the needle. Only now you can let go of the skin fold.
• The injection site must be pressed with a cotton ball soaked in alcohol.

Is it possible to inject yourself?

If you properly dilute Allokin-Alpha, follow all the norms and dosages, as well as the rules for administering the drug intramuscularly, then it can be administered independently.

At the same time, do not forget about cleanliness and thoroughly disinfect your hands, as well as the injection site. Syringes for each injection should be disposable.

If redness, bumps or suppuration are observed at the injection site of the needle, you should immediately consult a doctor. The appearance of various adverse symptoms is also a reason to visit a clinic or hospital.

The effectiveness of the drug: when to expect results?

The drug quickly enters the bloodstream, where it interacts with immune cells. An increase in the level of interferon by 2-2.5 times is noted already two hours after the injection and persists for 6-8 hours. Natural killers are activated after the administration of the drug for seven days.

special instructions

Allokin-Alpha is a very good and effective medicine, but some features of its use should be taken into account. This will help to avoid complications and possible adverse reactions of the body.

drug interaction

Allokin-Alpha can be used in combination with other drugs. Drug incompatibility is unlikely. In chronic herpes, the medication is prescribed along with antiviral drugs. For the treatment of hepatitis B in the acute stage, Allokin-Alpha is used in combination with basic therapy.

In general, the drug is well tolerated and can be combined with the following dosage forms:

• antibiotics;
• interferons and their inducers;
• antiviral drugs;
• antioxidants.

Pregnancy and lactation

It is not recommended to use Allokin-Alpha for pregnant women in any trimester of pregnancy. Nursing mothers medicine is also contraindicated.

Application in childhood

The drug is not prescribed for children from 0-12 years.

Alcohol compatibility

During treatment, it is not recommended to drink alcoholic beverages. This can lead to allergic reactions and dizziness. In addition, the effectiveness of the drug is reduced.

The duration of the course of treatment

For the treatment of infections caused by the human papillomavirus, the drug must be administered every other day. One injection includes 1 mg of the drug. The full course consists of 6 injections.

In case of recurrence of herpes, injections of the drug should be done every other day at a dosage of 1 mg. The course of treatment is 3 injections.

In moderate forms of hepatitis B, the solution is administered three times a week, 1 mg each. Treatment must be continued for three weeks. A total of 9 injections are needed.

Price category

Most often in pharmacies you can find Allokin-Alpha in packs of 3 and 6 ampoules. The price of a pack with three ampoules varies from 3450 r. up to 3950 rubles, with six – from 6970 rubles. up to 7500 r.

Contraindications and side effects

In the presence of autoimmune diseases, the drug is not recommended. This is due to insufficient knowledge of the effects of the drug on patients in this category.

In some cases, taking Allokin-alpha may be accompanied by adverse reactions of the body, such as:

• weakness;
• dizziness;
• the appearance of new condylomatous or herpetic eruptions.

Terms of dispensing from pharmacies

The drug can be purchased at a pharmacy, subject to the presentation of a prescription from a doctor.

Rules and duration of storage

Allokin-Alpha should be stored in a dark place, protected from light and direct sunlight. Keep away from children. The optimum temperature at which the drug will retain its properties and will not deteriorate is from 2-8 degrees above zero.

The shelf life of the medicine is two years. After this time, the drug should not be used.

What can be replaced, Russian counterparts

There are analogues of Allokin-alpha:

1. Panavir . The main active ingredient is hexose glycoside. Immunomodulatory and antiviral agent. After intravenous administration, it is found in the blood after five minutes. Released after 20 minutes. It is used for herpes, immunodeficiency states, cytomegalovirus infection, human papillomavirus infection, influenza. Contraindicated in case of individual intolerance, severe pathology of the spleen and kidneys, children under 12 years of age, during lactation.
2. Genferon . The active substance is interferon alpha , taurine, benzocaine. Candles  rectal and vaginal. Immunomodulating agent, interferon. Has a local effect. Antiviral, antibacterial, antiproliferative drug. In blood it is found in five hours after introduction. It is used for infectious and inflammatory diseases of the urogenital tract and acute bronchitis. Well tolerated, but individual intolerance to geneferon is possible. Safe during pregnancy 13-40 weeks.
3. Isoprinosine . Immunostimulating agent. The active substance is isoprinosine . It has an antiviral effect, increases blastogenesis, enhances the effect of antiviral agents and interferon-alpha. It is found in the blood after two hours. Rapidly metabolized and excreted through the kidneys. It is used for influenza, herpes, measles, papillomavirus and cytomegalovirus infections. Contraindicated in case of hypersensitivity to the drug, arrhythmia, gout, renal failure, urolithiasis, children under three years of age, pregnant and lactating women.
4. Imiquimod . Immunomodulating agent. The medication is available in the form of a cream. Immune response modifier, used to treat external warts on the genitals or perianal area. Contraindicated in children under 18 years of age and persons with hypersensitivity to imiquimod.
5. Epigen Intim . Spray for external use. The active ingredient is glycyrrhizic acid. Antiviral, immunostimulating agent. It also has anti-inflammatory, regenerating and antipruritic effects. It is used for infections caused by the herpes virus, human papillomavirus, cytomegalovirus. Allowed during pregnancy and lactation. Individual intolerance to Epigen Intim and contact dermatitis are possible.

Allokin-Alpha is an effective drug for the treatment of diseases caused by viruses and reduced immunity. He copes with the disease in a short time by activating the natural killer system in the body.

The drug acts localized in the focus of inflammation. The drug should be used, taking into account contraindications. With individual intolerance and the appearance of adverse reactions, the administration of the drug must be discontinued.