Содержание:
- 1 Introduction
- 2 In what cases are immunomodulators prescribed?
- 3 Pros and cons of using the drug
- 4 The role of suppositories in improving immunity and fighting the HPV virus
- 5 The mechanism of action of the drug on the body
- 6 When is it prescribed for children?
- 7 Instructions for use
- 8 Side effects and contraindications
- 9 The best pharmaceutical preparations
- 10 Selection Guide
Introduction
Immunomodulatory drugs enhance the protective functions of the body. They are prescribed for infectious and viral diseases to prevent the development of complications.
Usually they are used after a long cold and other respiratory diseases.
In what cases are immunomodulators prescribed?
Suppositories are most often prescribed as an immunomodulator, since they have practically no contraindications, they are suitable for both adults and children.
Rectal
Immunomodulators in the form of rectal suppositories are prescribed to increase immunity functions in:
- prevention of complications after surgical interventions;
- frequent or prolonged SARS;
- complex treatment of viral and bacterial diseases;
- the need to strengthen local immunity, especially in the field of gynecology.
Vaginal
Vaginal suppositories are most often prescribed by a gynecologist for the purpose of:
- treatment of dysbacteriosis and restoration of the vaginal microflora;
- strengthening the local immune system;
- prevention of recurrence and complications of the disease.
Pros and cons of using the drug
Positive aspects of immunomodulators:
- when immunity is weakened, they strengthen it by stimulating increased production of human interferon, a protein that blocks the reproduction of viruses;
- suppositories are easy to use;
- compatible with many drugs;
- almost complete absence of contraindications and side effects;
- are well absorbed by the body and have a wide spectrum of action;
- May be used in children under one year of age.
There are not so many disadvantages of immunomodulatory suppositories:
- the cost is higher than that of tablets and other types of drugs;
- improper appointment and use of immunomodulators is fraught with the opposite effect.
The role of suppositories in improving immunity and fighting the HPV virus
With the human papillomavirus (HPV), immunomodulatory drugs help the body fight viruses and increase the chances of self-healing. Candles are also prescribed in the fight against dangerous strains of the virus that provoke the development of cervical cancer.
The drugs contain the virus, eventually completely suppressing its activity.
The mechanism of action of the drug on the body
The main component of the immunomodulator is human interferon. It activates the entire immune system, and does not act selectively: the activity of antibodies responsible for resistance to infections increases.
The duration of the use of drugs is unlimited. Their use is possible for several years, if necessary.
When is it prescribed for children?
Immunomodulators are most often prescribed for children in suppositories in the following cases:
- with long and severe courses of colds;
- to prevent acute respiratory viral infections, cytomegalovirus, herpes viruses, hepatitis, chlamydia;
- in inflammatory processes;
- to prevent complications after surgery.
Instructions for use
Suppositories are administered rectally or intravaginally in adults, in children under 6 years old – only rectally. The method and dosage is prescribed by the attending physician, based on the diagnosis, the severity of the disease.
With rectal administration, you must first empty the intestines and carry out hygiene procedures. With intravaginal application, suppositories are administered in a supine position at bedtime.
Side effects and contraindications
There are no side effects and contraindications as such, only rare individual reactions to the constituent components of the immunomodulator:
- redness;
- swelling;
- itching.
The best pharmaceutical preparations
The main active component of most immunomodulators is recombinant human interferon . But there are some differences in the composition, due to which certain drugs are prescribed depending on the diagnosis.
Galavit
It is prescribed as an immunomodulatory, anti-inflammatory, antioxidant agent:
- strengthens the immune system;
- reduces inflammation;
- protects against recurrence of viral and bacterial diseases;
- prevents the development of complications.
The drug quickly penetrates into the focus of inflammation, blocks inflammation for 6–8 hours, reduces the intensity of symptoms of fever, pain, and swelling. Galavit neutralizes oxidation products, reduces the severity of intoxication and improves the patient’s condition.
Depantol
Suppositories for intravaginal administration. One suppository contains 16 mg of chlorhexidine bigluconate, 100 mg of dexpanthenol, and additionally a mixture of polyethylene oxides.
Due to its composition, Depantol is used to treat:
- ureaplasma, chlamydia, gardnerella, gonorrhea, escheria, streptococcus, etc.;
- acute and chronic vaginitis, including candidiasis;
- cervititis;
- cervical erosion.
Also, the drug is prescribed for the regeneration of the mucous tissues of the vagina after aggressive treatment of erosions, after childbirth and surgery.
In the treatment of mixed bacterial-fungal infections, Depantol is used as part of complex therapy.
Depantol:
- relieves inflammation;
- reduces swelling;
- restores damaged tissues.
Vaginorm-S
Product properties:
- normalizes acidity, thanks to ascorbic acid in the composition;
- inhibits pathogens;
- improves immunity;
- fights anaerobic microbes in the vagina;
- normalizes the microflora of the vagina.
Prescribed for diagnosis:
- bacterial vaginosis;
- nonspecific vaginitis;
- vaginal dysbiosis.
Vaginorm C is available as vaginal tablets, often referred to as suppositories. When doctors or pharmacists say “candles Vaginorm C”, it is vaginal tablets that are meant. The drug has no other dosage form (gels, suppositories, etc.).
Acylact
The preparation contains three different strains of lactic acidophilus bacteria. Acylact is a probiotic that regulates the content of microflora in the vagina.
Lactobacilli, which are part of the drug, destroy the pathogenic flora: staphylococci, E. coli and other harmful bacteria.
Acylact:
- normalizes the microflora of the intestine and vagina;
- restores the general condition of the body;
- improves metabolism;
- maintains acid balance;
- eliminates the possibility of developing infections;
- strengthens general and local immunity.
Bifidumbacterin
The drug is prescribed for the treatment of:
- vaginal dysbacteriosis;
- disorders of the intestinal microflora;
- negative consequences of taking antifungal agents;
- vaginal candidiasis (thrush).
Bifidumbacterin normalizes the microflora of the vagina and intestines, inhibits the development of pathogenic microorganisms and populates the microflora with beneficial bifidobacteria.
Vagilak
Vagilak are phytocandles, consisting of calendula flowers, with the following properties:
- restore the natural microflora and suppress pathogens;
- have an anti-inflammatory effect;
- has antioxidant functions, heals and restores the cellular structure of the vaginal epithelium;
- fight bacterial vaginosis.
Viferon
The drug has an immunomodulatory, antiproliferative and antiviral effect, blocks the reproduction of viruses, increases the activity of macrophages and the cytotoxicity of lymphocytes.
When choosing the right dosage, it is also suitable for newborns, because it does not provoke the development of complications, does not cause adverse reactions, except for individual intolerance to any component of the drug.
Genferon
The composition includes interferon, benzocaine, taurine. Genferon is prescribed as an antiviral, antimicrobial, immunomodulatory, regenerating, antioxidant, anti-inflammatory, analgesic agent.
The suppositories are suitable for rectal and vaginal use. It is prescribed for children over 7 years old and adults. Contraindicated in the first trimester of pregnancy, and in the later stages can only be used under medical supervision.
Appointed in the following cases:
- SARS, influenza;
- pneumonia;
- infectious and inflammatory diseases of newborns, including premature ones: meningitis, sepsis, chlamydia, herpes, cytomegalovirus, enterovirus, candidiasis, mycoplasmosis;
- chronic viral hepatitis B, C, D;
- infectious and inflammatory diseases of the urogenital tract;
- herpetic infection of the skin and mucous membranes.
Genferon contains ready-made antibodies to many viruses and bacteria.
Polyoxidonium
A drug:
- stimulates the production of antibodies;
- activates phagocytic cells and natural killers;
- restores immunity in case of protracted and constantly recurring diseases;
- helps in recovery after chemotherapy, the use of cytostatics, hormones;
- has an antioxidant and detoxifying effect.
Polyoxidonium can be applied rectally and vaginally. Suitable for use by children over 6 years of age. There are no data on the safety of use during pregnancy and lactation, so the use of this category of patients is prohibited. Polyoxidonium does not have a teratogenic and carcinogenic effect on the body.
Kipferon
Product properties:
- immunomodulatory;
- antiviral;
- anti-inflammatory;
- antichlamydial;
- antibacterial.
Kipferon stimulates the immune system, acts directly on pathogens.
It is prescribed for the treatment of:
- herpeviruses;
- rotaviruses;
- chlamydia;
- enterobacteria;
- staphylococci and other pathogens at the cellular level.
Selection Guide
When prescribing the drug, the doctor focuses primarily on his experience: if the drug has already helped previous patients with a similar diagnosis. You can also learn about the effectiveness of the drug from the reviews. It is important to pay attention to the results of clinical trials of the drug and the presence of a proven mechanism of action.
With the right appointment, immunomodulators are a good help to the immune system in the fight for the health of your body. Due to the use of drugs in complex therapy, the duration of the disease is reduced, and the consequences after taking other medications are reduced.
