Polyoxidonium is a drug that has a number of medicinal properties. It is an immunomodulator , antioxidant, has a pronounced anti-inflammatory and detoxifying effect.
When using this drug, the main rule for successful treatment is the competent preparation of an injection solution using specific solvents.
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Injection forms of the drug and composition
Polikosidoniy is available in the form of a lyophilisate for solution for injection and intranasal use. It looks like a white mass of porous structure and has a yellowish tint.
The drug consists of:
- The active ingredient is azoximer bromide. Its content is 3 or 6 mg in one vial.
- auxiliary substances. Such as mannitol and povidone K17.
Indications for use
Polyoxidonium has a wide list of indications and can be used as monotherapy for:
- prevention of influenza and acute respiratory viral diseases;
- prevention of complications after operations (bacterial infections).
Also, the drug can be used as part of complex therapy in the following cases:
- with infections of a viral or bacterial nature of the organs of the respiratory, reproductive and urinary systems;
- with allergic diseases that are complicated by the addition of bacteria, viruses or fungi;
- with rheumatoid arthritis;
- with tuberculosis;
- with intestinal dysbacteriosis;
- as well as with cancerous tumors during chemotherapy, radiation and after them.
How to prepare a solution with Novocaine?
According to the standard solution preparation scheme, Polyoxidonium is not diluted with novocaine. However, in practice, doctors recommend that some patients use Novocain in order to reduce the pain of the procedure. The decision on whether this can be done is made by the doctor for each individual.
In the presence of pain at the injection site, the drug can be dissolved in 1 ml of a 0.25% solution of Novocaine (Procaine). It is important to make sure that the person does not have intolerance to this remedy.
Can this be done with Lidocaine?
No, dilution with this drug is unacceptable.
Reference. Perhaps the simultaneous use of Polyoxidonium and Lidocaine, but in different syringes. To do this, a Polyoxidonium solution is prepared in one syringe according to all the rules specified in the instructions.
The other is filled with 1 ml of Lidocaine. It is administered first, after which an injection of Polyoxidonium is carried out. In this case, we are talking only about intramuscular injection.
Combinations with other drugs
The combination of Polyoxidonium with water for injection or 0.9% saline (NaCl) is optimal.
When using the drug for the purpose of intravenous administration, the use of protein-containing solutions is unacceptable.
How to dilute the drug for intramuscular injection?
A feature of the preparation of the Polyoxidonium solution is the swelling stage, when the powder and liquid begin to interact with each other.
Adults
The powder contained in the vial in an amount of 6 mg should be dissolved in 2 ml of water for injection or 0.9% NaCl. After that, leave the drug for 2 minutes.
During this time, the resulting mixture swells. The last stage of preparation will be shaking the bottle with rotational movements.
children
The preparation method is similar, the difference lies in the content of the components used. So, the amount of Polyoxidonium should be 3 mg, and the amount of solvent (water for injection or saline) should be 1 ml.
Side effects and contraindications
Side effects:
- Local reactions in the form of soreness, redness and thickening of the skin.
- Systemic side effects. Such as: an increase in body temperature to subfebrile values (37.0 ° C-37.3 ° C), slight anxiety, chills. As a rule, such symptoms are observed within the first hour after the administration of the drug.
- Perhaps an allergic reaction. It manifests itself in the form of swelling and redness of the mucous membranes (lacrimation of the eyes, swelling of the oral mucosa), as well as itching of the skin and the appearance of a rash on them.
Contraindications are that the use of the drug is unacceptable when:
- individual intolerance to its components;
- acute renal failure;
- pregnancy, lactation;
- age up to 6 months.
