Indications for use of Polioxidonium suppositories, instructions for children and adults, features of the drug

In pharmacies, you can find many immunomodulatory drugs, among which are Polyoxidonium candles.

Doctors often prefer suppositories because they have a minimum of contraindications and practically no side effects.

 

Release form, composition and packaging, abstract

Candles Polyoxidonium have a torpedo shape of a light yellow hue with an unexpressed smell of cocoa butter. On the cut of the suppository there is an air rod or a funnel-shaped recess.

Polyoxidonium candles consist of

• active substance: azoximer bromide 12 mg or 6 mg;
• auxiliary components: mannitol, povidone K17, cocoa butter.

In one contour cell plate, 5 suppositories are produced.

Pharmacological action, is the drug used to increase immunity?

Azoximer bromide, the main substance, is considered universal in action. It belongs to the anti-inflammatory, detoxifying agent, and is also an immunomodulator  and antioxidant.

The drug is prescribed not only to fight viruses, but also to prevent, maintain immunity in people with cancer.

Pharmacokinetics

Azoximer bromide, when administered rectally, enters the bloodstream within 1-1.5 hours and is distributed throughout the body. The drug decomposes to oligomers, which are excreted by the kidneys after 36 hours.

Indications for use

The drug is prescribed for adults, adolescents and children from 6 years of age. Therapists and pediatricians prescribe Polyoxidonich in the following situations:

• colds, viral and infectious diseases, such as acute respiratory infections, SARS and influenza;
• prophylaxis during the season of increased morbidity;
• chronic diseases caused by infections, viruses and bacteria during exacerbation of symptoms or during remission;
• urogenital diseases;
• tuberculosis in various forms of the disease;
• autoimmune diseases;
• allergy;
• oncological diseases;
• rehabilitation of people who suffer from acute respiratory viral infections and acute respiratory infections more than 4 times a year.

At what age is the 6 mg dosage prescribed?

Doctors prescribe Polyoxidonium suppositories with a dosage of the active substance of 6 mg to children from 6 years of age.

When prescribing to children of a younger age, the doctor will prescribe a lyophilisate, which can be dripped or injected from the age of 6 months of the child’s life, or tablets prescribed for children older than 3 years.

Instructions for use of suppositories

The drug is prescribed for children, adolescents and adults. In order for Polyoxidonium  to help cope with the disease, you should follow the instructions for use.

Adults

Depending on the diagnosis, the recommended dosage for patients over 18 years of age:

1. For infectious and colds during an exacerbation , as well as gynecological diagnoses – suppositories “Polyoxidonium 12 mg” 1 time per day for three days, after 10 suppositories 1 piece every two days.
2. For urological diseases – 1 suppository per day for 10 days.
3. Pulmonary tuberculosis – first 1 suppository per day, then 40 days 1 suppository every other day. With maintenance therapy, 6 mg of the active substance 2-3 times a week.
4. Oncological diseases – 1 suppository 2 times a week, general course – 20 suppositories.
5. Allergy – 1 suppository per day for 10 days.

For the prevention of various diseases, 1 suppository is used every 1-2 days, the general course should consist of 10 suppositories.

How to apply to children?

Suppositories for children are used only in a dose of 6 mg.

The standard instructions for using the drug are as follows:

1. Chronic diseases – the first three days, 1 suppository per day, then 1 suppository every two days. The duration of the entire course is 17 days.
2. Urological diseases and acute inflammatory processes – 1 piece for 10 days.
3. Tuberculosis – the first three days of 1 suppository, then every other day for 40 days.
4. Chemotherapy – three days before therapy, one suppository every day, then every other day for 40 days.
5. Allergy – 1 suppository per day. Duration 10 days.

For prevention – 1 candle per day. The course should consist of 10 suppositories.

During pregnancy and breastfeeding

It is quite difficult for women in position to select medicines. In no case should this be done on its own, the attending physician should assess the possible harm and benefit when prescribing Polyoxidonium suppositories.

Experiments to identify the possibility of prescribing the drug were carried out on animals. As a result, neither the females nor the fetus were found to have any abnormalities.

However, clinical experiments on humans have not been conducted, so the remedy is prohibited for expectant mothers. There is also no information on the possibility of using the drug during lactation.

If there are no alternative medicines, then during breastfeeding the baby is transferred to artificial feeding, and only after that Polyoxidonium suppositories are prescribed.

Is an overdose possible?

Cases of overdose with Polyoxidonium suppositories in medical practice are unknown.

Are there side effects?

Due to individual intolerance to certain substances contained in the preparation, itching may begin. In this case, the drug is canceled.

In what cases is the drug contraindicated?

Suppositories Polyoxidonium have several contraindications:

• pregnancy and lactation;
• age up to 6 years;
• intolerance to the substances of the drug.

Use for impaired renal or hepatic function

In the presence of diseases of the liver or kidneys, the drug is taken strictly according to the doctor’s prescription, since clinical experiments in this area have not been conducted.

Drug interactions with other drugs

The manufacturer allows the possibility of combining the drug with antibiotics, antihistamines and antiviral drugs.

special instructions

For patients taking the drug, the manufacturer advises:

• stop the drug immediately, you do not need to do it gradually, reducing the dosage;
• if the medication was missed, it is worth continuing the treatment  according to the given scheme;
• in no case do not take the drug after the expiration date.

Conditions and terms of storage of the medicine

Store suppositories in a cool place at a temperature of + 2 + 15 degrees Celsius. Shelf life – 2 years.

Terms of dispensing from pharmacies

Candles Polyoxidonium is an over-the-counter drug, therefore it is freely sold in many pharmacies.

Analogues

Polyoxidonium suppositories have a rather unique structure, so it is impossible to find a drug with similar compositions. There are drugs with a similar therapeutic effect, but with a different composition, for example:

• Galavit.
• Methyluracil.
• Imunofan.

Therefore, if your pharmacy does not have Polyoxidonium, consult your doctor to prescribe another drug.

Reviews of doctors and patients, price

Doctors and parents who use suppositories  for their children speak very positively about the drug.

Among the advantages of the Polyoxidonium suppository, immunologists note a wide range of applications, safety for the body of children, a small number of contraindications and side effects.

Moms note that the therapeutic effects from the use of candles appear very quickly, and the disadvantages include the high cost of the medication – about 700–900 rubles .